NURS 6630 MIDTERM & FINAL EXAM STUDY GUIDES NURS 6630 Midterm & Final Exam Study Guides
NURS 6630 MIDTERM & FINAL EXAM STUDY GUIDES
NURS 6630 MIDTERM EXAM STUDY GUIDE
Non-compliant patients
Neurotransmitters
Gene Expression
Cytochrome P450 Enzyme System
Pharmacokinetics
Mechanisms of receptors including:
o G-Protein linked receptors
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NURS 6630 Midterm & Final Exam Study Guides
o nicotine cholinergic
o serotonin
o dopamine
o norepinephrine
o D2 receptors
o glycine receptors
o ionotropic receptors
Medications classifications – Full agonists, antagonists, partial agonist, and inverse agonists
Therapeutics, side effects, dosing, use, and special populations for medications to treat
o Psychosis and schizophrenia
o bipolar disorders
o depression
o mania
o paranoid psychosis
o panic disorders
o fibromyalgia
o smoking cessation
o Parkinson’s disease
o anxiety. 6630 Midterm & Final Exam Study Guides.
o stress
o PTSD
How to identify improvement in a patient following administration of medication
System-based approaches to treatment
MAO inhibitors
Stahl’s Essential Psychopharmacology
Chapter 1 – Chemical Neurotransmission
Anatomical versus chemical basis of neurotransmission
Signal transduction cascades
Epigenetics
Chapter 2 – Transporters, receptors, and enzymes as targets of psychopharmacological drug action
Neurotransmitter transportation as targets of drug action
G-protein-linked receptors
Enzymes as targets of psychotropic drugs
Cytochrome P450 drug metabolizing enzymes as targets of psychotropic drugs
Chapter 3 – Ion channels as targets of psychopharmacological drug action
Ligand-gated ion channels as targets of psychopharmacological drug action
Voltage-sensitive ion channels as targets of psychopharmacological drug action
Ion channels and neurotransmission. NURS 6630 Midterm & Final Exam Study Guides.
Chapter 4 – Psychosis and schizophrenia
Symptom dimensions in schizophrenia
Neurotransmitters and circuits in schizophrenia
Neurodevelopment and genetics in schizophrenia
Neuroimaging circuits in schizophrenia
Chapter 5 – Antipsychotic agents
Conventional antipsychotics
Atypical antipsychotics
Links between antipsychotic binding properties and chemical actions
Pharmacologic properties of individual antipsychotics: the pines, the dones, two pips and a rip plus more
Antipsychotics in clinical practice. NURS 6630 Midterm & Final Exam Study Guides.
Future treatments for schizophrenia
Chapter 6 – Mood disorders
Description of mood disorders
The bipolar spectrum
Can unipolar depression be distinguished from bipolar depression?
Are mood disorders progressive?
Neurotransmitters and circuits in mood disorders
Stress and depression
Symptoms and circuits in depression
Symptoms and circuits in mania. NURS 6630 Midterm & Final Exam Study Guides.
Neuroimaging and mood disorders
Chapter 7 – Antidepressants
General principles of antidepressant action
Antidepressant classes
Augmenting antidepressants
How to choose an antidepressant
Future treatments for mood disorders
Stahl’s Illustrated Guide – Anxiety, Stress, and PTSD
Chapter 4 – First line medications for PTSD
Pharmacological Treatments
SSRIs
Chapter 5 – Second-line, adjunct, and investigational medications for PTSD
Second-line Medications
Adjunct Medications. NURS 6630 Midterm & Final Exam Study Guides.
Investigational Medications
NURS 6630 FINAL EXAM STUDY GUIDE
Therapeutics, side effects, dosing, use, and special populations for medications to treat
o psychotic aggression
o psychotic behaviors
o psychosis and aggression
o impulsive symptoms
o ADHD
o mood disorders
o fibromyalgia
o chronic pain
o migraines
o shingles
o Alzheimer’s disease
o dementia
o PTSD
o Premenstrual dysphoric disorder (PDD)
o Irritable bowel syndrome
o diabetic peripheral neuropathic pain
o addictions
o smoking cessation
o Kleptomania. NURS 6630 Midterm & Final Exam Study Guides.
o Impulsive aggression
o Insomnia and sleep disorders
o
Stahl’s Essential Psychopharmacology
Chapter 10 – Chronic pain and its treatment
What is pain?
Neuropathic pain
Descending spinal synapses in the dorsal horn and the treatment of chronic pain
Targeting sensitized circuits in chronic pain conditions
Targeting ancillary symptoms in fibromyalgia
Chapter 11 – Disorders of sleep and wakefulness and their treatment
Neurobiology of sleep and wakefulness
Insomnia and hypnotics. NURS 6630 Midterm & Final Exam Study Guides.
Excessive daytime sleepiness (hypersomnia) and wake-promoting agents
Chapter 12 – Attention deficit hyperactivity disorder and its treatment
Symptoms and circuits: ADHD as a disorder of the prefrontal cortex
ADHD as a disorder of inefficient “tuning” of the prefrontal cortex by dopamine and norepinephrine
Neurodevelopment and ADHA
Treatment
Chapter 13 – Dementia and its treatment
Causes, pathology, and clinical features of dementia
Three stages of Alzheimer’s disease. NURS 6630 Midterm & Final Exam Study Guides.
Targeting amyloid as a future disease-modifying treatment of Alzheimer’s disease
Targeting glutamate
Treatments for psychiatric and behavioral symptoms in dementia
Other proposed targets for dementia
Chapter 14 – Impulsivity, compulsivity, and addiction
Overview of impulsive-compulsive disorders
Neurocircuitry and the impulsive-compulsive disorders
Substance addictions
Obesity as an impulsive-compulsive disorder
Stahl’s Illustrated Guide – Chronic Pain and Fibromyalgia
Chapter 5 – Pain drugs. NURS 6630 Midterm & Final Exam Study Guides.
Stahl’s Illustrated Guide – ADHA
Chapter 4 – ADHD treatments
Stahl’s Illustrated Guide – Substance Use and Impulsive Disorders
Chapter 10 – Disorders of impulsivity and compulsivity
Stahl’s Illustrated Guide – Violence
Chapter 3 – Treatment of violence and aggression
Pharmacological Interventions for ADHD
Table B. KQ2: Long-term (>1 year) effectiveness of interventions for ADHD in people 6 years and older
Pharmacological Interventions
Article
Clancy, C.M., Change, S., Slutsky, J., & Fox, S. (2011). Attention deficit hyperactivity disorder: Effectiveness of treatment in at-risk preschoolers; long-term effectiveness in all ages; and variability in prevalence, diagnosis, and treatment. Table B. KQ2: Long-term(>1 year) effectiveness of interventions for ADHD in people 6 years and older. NURS 6630 Midterm & Final Exam Study Guides.
