Infectious Diseases Pharmacology

Unit 5: Infectious Diseases Pharmacology

Infectious Disease Pharmacology
Infectious Disease Pharmacology

Welcome to Unit 5 of Advanced Pharmacology
A large part of primary care is treating infectious diseases. Antibiotics, antiviral’s, and antifungals are anti-infective agents that you will need to be highly familiar and develop a comfort zone of knowledge and application of various agents. Spend time on these modules and gather additional resources to aid in your success. Some of those resources are listed in the optional books section of the syllabus. Categorizing and time-effective agents into classes are most helpful in understanding their mechanism of action. Sensitivity and resistance are factors to consider when prescribing anti-infected agents. In addition, there are steps in antimicrobial drug selection to consider when a diagnosis or differential diagnosis has been made. As you begin to put it all together, you will see that an accurate diagnosis or differential diagnosis is crucial to rational drug selection. Special population characteristics also come into consideration.
Unit Learning Objectives

Examine the principles of pathophysiology and therapeutics that direct the pharmacotherapeutic interventions for infectious diseases
Analyze the pharmacokinetic and pharmacodynamic actions of agents used for management of infectious diseases
Apply the evidence for pharmacotherapeutic interventions in a patient with infectious diseases
Apply critical-thinking processes to the management and evaluation of expected effects and potential adverse effects of pharmacodynamic agents.

Week 7/Unit 5 “To Do” List

High-Yield Med Review Infectious Disease Quiz due Sunday of Week 7
Shadow Health Focused Exam: Pediatric GAS Pharyngitis due Sunday of Week 7
Shadow Health Anti-infectives Concept Lab due Sunday of Week 7
Prepare for Unit 4 & 5 Exam next week!

Learning Materials
Learning Materials

Lectures & E-Book

Busti, A. J. (2022). NP Curriculum Support-Advanced Pharmacology for NPs. MedEducation, LLC.

INFECTIOUS DISEASES PHARMACOLOGY

Penicillin Agents
Cephalosporins
Fosfomycin
Macrolides
Fluroquinolones
Antibiotics-other
Anaerobic Agents
Influenza-Antiviral Review
Antifungals

SPECIAL TOPICS IN PHARMACOLOGY

Drug Allergies and Cross Reactivity – Penicillin Allergies
Drug Allergies and Cross Reactivity – Sulfa Allergies

ADVANCED DRUG CLASS REVIEW TOPICS

Ophthalmic Antibiotics for Bacterial Eye Infections

Optional Learning Resources
Media

Khan Academy Medicine. (2015, June 26). Treating HIV: Antiretroviral drugs, infectious disease [Video]. YouTube. https://www.youtube.com/watch?v=GR9d9wrOl5E
Parkes, C. (2019, June 26). Nursing pharmacology – TB, antiprotozoal, antifungal and antiviral meds [Video]. YouTube. https://www.youtube.com/watch?v=gEcQrLpdi1I
Speed Pharmacology. (2018, March 26). Pharmacology – antibiotic – cell wall and membrane inhibitors (made easy) [Video]. YouTube. https://www.youtube.com/watch?v=mMk6VWVpRpo
Speed Pharmacology. (2018, May 3). Pharmacology – antibiotics – DNA, RNA, folic acids, protein synthesis inhibitors [Video]. YouTube. https://www.youtube.com/watch?v=5HQmvQJWzNY

Websites

Gilbert, D. N., Chambers, H. F., Eliopoulos, G. M., Saag, M.S., & Pavia. A. T. (2017). The Sanford guide to antimicrobial therapy (47th ed.). Sperryville, VA: Antimicrobial Therapy.

Note: This resource is also available in electronic book formats and mobile formats at https://store.sanfordguide.com/antimicrobial-therapy-c2.aspx

Hollier, A. (2011). Pediatric dosage cards. Lafayette, LA: Advanced Practice Education Associates.

Note: These dosage cards can be purchased at https://www.apea.com/clinical-resources/pediatric-dosage-cards

Khan Academy. (2018n). Infectious diseases. Retrieved March 11, 2021, https://www.khanacademy.org/science/health-and-medicine/infectious-diseases

HYMR Quiz – Infectious Disease

Following review of all assigned lectures and correlating E-book chapters in High Yield Med Review, you will complete the module quiz in the HYMR platform.

From the Dashboard select “EXAMS”
Navigate to the “Infectious Diseases – Self Assessment”
Click “Take Exam”

You will have one attempt to complete 10 questions in 15 minutes. Once completed, please take a screen shot of your score and upload to this assignment tab for grading. This quiz is worth 20 points, so based on your % score you will receive the correlating points below.

100%

20 points

90%

18 points

80%

16 points

70%

14 points

60%

12 points

50%

10 points

40%

8 points

30%

6 points

20%

4 points

10%

2 points

No submission

0 points

*Please note, faculty are able to view your time and activity in HYMR.*

Shadow Health: Concept Lab – Anti-infectives

The purpose of this Shadow Health Concept Lab assignment is to help you achieve the following Course Learning Outcomes 1-5.
Assignment:
This week you will participate in a Shadow Health Concept Lab pertaining to anti-infective medications. This will allow you to learn about pharmacological concepts related to commonly administered anti-infective drugs. This module should take approximately 30 minutes to complete.

What to Submit:
Upon completion of the assignment:

Submit your completion certificate
Submit your reflection response to the questions below

Reflection Response Instructions: Submit a 1 page reflection response to the questions below. Please use APA format and include one scholarly reference.

What are some available resources/guidelines that you will use to help select appropriate antibiotics? Give brief overview of how this will apply to your NP practice.

Shadow Health Technical Support
If at any time you have any questions or encounter any technical issues regarding the Digital Clinical Experience, please contact the Shadow Health support specialists by visiting the Learner Support Page at http://support.shadowhealth.com for contact information and hours. You may email the Learner Support team directly at [email protected] at any time or by calling 800.860.3241.

Shadow Health: Focused Exam: Pediatric GAS Pharyngitis

The purpose of this Shadow Health Focused Exam assignment is to help you achieve Course Learning Outcomes 1-5.

Assignment:
This assignment provides the opportunity to conduct a focused exam on a pediatric patient who presents with Group A Streptococcal Pharyngitis. You will interview Sophia Haddad and her father, Omar, using therapeutic communication and obtain enough subjective data to determine the appropriate pharmacological therapy for her condition. After the patient exam, you will select the most appropriate medication for Ms. Haddad and educate her father on how to safely administer it and care for Sophia while she is sick. If applicable, you will write a prescription for the selected medication.

What to Submit:
Upon completion of the assignment, submit your completion certificate/lab pass that shows the DCE score to this assignment link..

Shadow Health Grading
All assignments will be graded using the DCE Score. Reopening and multiple attempts are allowed so the student can submit the best score for grading. Each student will submit the “lab pass” showing their DCE score to the designated assignment tab in Blackboard. Grading will be based on the DCE score received on the assignment that correlates with the points allocated in the table below. An incomplete assignment will result in the grade of zero. Faculty will monitor student engagement within the Shadow Health platform to ensure active participation to complete all the assignment requirements.

DCE Score

Points

95-100

90-94

85-89

80-84

Below 79

No submission

Assignment Due Date: Sunday of Week 6

Unit Conclusion
Unit Conclusion

As we wrap up week 7 of Advanced Pharmacology, we covered a large amount of information in a common area of primary care, which is treating infectious diseases. I hope you continue to spend time on this material and gather additional resources to aid in your success. As you continue to put it all together, you will see that an accurate diagnosis or differential diagnosis is crucial to rational drug selection.

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