Endocrine Pharmacology

Unit 4: Endocrine Pharmacology

Exam 1 Due this Week!
Exam 1 Due this Week!

Exam 1 will be available Thursday 10/6 – Saturday 10/8, please plan accordingly to complete the exam during this timeframe.

Study Guide Exam 1 Advanced Pharmacology

Understand pharmacokinetics and pharmacodynamics
Be aware how medications are absorbed and what are factors or variables in drug absorption
Know pregnancy risk categories
Understand CYP 384 isoenzymes for metabolism
Understand drug steady state
Understand the following drug classes ace inhibitors mechanism of action and side effects, beta blockers mechanism of action and side effects, pacer dilators mechanism of action and potential side effects
Anti-hypertensive medication mechanism of action, side effects, and precautions
Heart failure-drugs used to treat
Angina and drugs used to treat
Aspirin therapy
Be knowledgeable of the medications to treat hyperlipidemia, know side effects, when to check labs and what labs to check for follow up
Anticoagulation medication mechanism of action, side effects, and precautions

Enter the exam through Respondus and navigate to the tab titled “Exams” to access Exam 1.

Endocrine Pharmacology
Endocrine Pharmacology

Welcome to Unit 4 of Advanced Pharmacology
The endocrine system is vast, and drugs used to treat disorders are numerous as well. Drug classes categorize the mechanism of actions and the subtle differences between in-class drugs. As 1 in 10 Americans has Diabetes, this is important disease management to understand and there are many pharmacologic choice for management to avoid long-term complications. Therefore, a strong understanding of pathophysiology is critical as we examine how these drug work to treat endocrine disorders.
*Please note this unit runs over 2 weeks.*
Unit Learning Objectives

Examine the principles of pathophysiology and therapeutics that direct the pharmacotherapeutic interventions for endocrine system and pertaining to diabetes management.
Analyze the pharmacokinetic and pharmacodynamic actions of agents used for management of endocrine system and diabetes management.
Apply the evidence for pharmacotherapeutic interventions in a patient with an endocrine system and diabetes management.
Apply critical-thinking processes to the management and evaluation of expected effects and potential adverse effects of pharmacodynamic agents.

Week 5 & 6/Unit 4 “To Do” List

Complete the HYMR Endocrine Quiz (week 5)
Unit 1-3 Exam available Thursday 9/29 – Saturday 10/1 (Must access via Respondus) (week 5)
Complete Shadow Health Focused Exam: HTN and Type 2 Diabetes (week 6)
Complete Shadow Health Antidiabetics Concept Lab (week 6)

Learning Materials
Learning Materials

Lectures & E-Book

Busti, A. J. (2022). NP Curriculum Support-Advanced Pharmacology for NPs. MedEducation, LLC.

ENDOCRINE PHARMACOLOGY (Week 5 & covers quiz content)

Insulin Therapy Review
Sulfonylurea & Meglitinides Review
Alpha Glucosidase Inhibitors Review
Biguanides (Metformin) Review
TZDs Review
DPP-4 Inhibitors Review
SGLT2 Inhibitors Review
GLP-1 Receptor Agonists Review
Amylin Analogs Review
Hypoglycemia
Corticosteroids Review–Pharmacology
Corticosteroids Review–Application

ENDOCRINOLOGY-DIABETES MELLITUS (Week 6 & not on quiz)

Type 2 Diabetes Mellitus
GLP-1 Agonists & SGLT2 Inhibitors in CKD
GLP-1 Agonists & SGLT2 Inhibitors in CVD
GLP-1 Agonists & SGLT2 Inhibitors in hF
Diabetes Mellitus Type 1 Diabetes Mellitus (T1DM)

ENDOCRINOLOGY-OBESITY (Week 6 & not on quiz)

Obesity-General Overview
Obesity-Lifestyle Management
Obesity-Obesity in CVD

Optional Learning Resources:
Media

Khan Academy (Producer). (2015). What is diabetes mellitus? [Video]. https://www.khanacademy.org/science/health-and-medicine/endocrine-system-diseases/diabetes/v/what-is-diabetes-mellitus?ref=health_staff_picks
Speed Pharmacology. (2017, September 24). Pharmacology – drugs for diabetes (made easy). [Video]. YouTube. https://www.youtube.com/watch?v=LWDQyaKVols

Websites

American Diabetes Association®. (2020). Get a handle on diabetes medication. Retrieved from https://www.diabetes.org/diabetes/medication-management
Khan Academy. (2018). Endocrine system diseases. Retrieved from https://www.khanacademy.org/science/health-and-medicine/endocrine-system-diseases
The American Association of Clinical Endocrinologists. (2018). Retrieved from https://pro.aace.com/

Note: Familiarize yourself with the AACE guidelines.

HYMR Quiz – Endocrine

Following review of all assigned lectures and correlating E-book chapters in High Yield Med Review, you will complete the module quiz in the HYMR platform.

From the Dashboard select “EXAMS”
Navigate to the “Endocrinology-Self Assessment”
Click “Take Exam”

You will have one attempt to complete 10 questions in 15 minutes. Once completed, please take a screen shot of your score and upload to this assignment tab for grading. This quiz is worth 20 points, so based on your % score you will receive the correlating points below.

100%
20 points

90%
18 points

80%
16 points

70%
14 points

60%
12 points

50%
10 points

40%
8 points

30%
6 points

20%
4 points

10%
2 points

No submission
0 points

*Please note, faculty are able to view your time and activity in HYMR.*

Shadow Health: Concept Lab – Antidiabetics

The purpose of this Shadow Health Concept Lab assignment is to help you achieve the following Course Learning Outcomes 1-5.
Assignment:
This week you will participate in a Shadow Health Concept Lab pertaining to antidiabetic agents.This will allow you to learn about pharmacological concepts related to commonly administered antidiabetic drugs. This module should take approximately 30 minutes to complete.

What to Submit:
Upon completion of the assignment:

Submit your completion certificate
Submit your reflection response to the questions below

Reflection Response Instructions: Submit a 1 page reflection response to the questions below. Please use APA format and include one scholarly reference.

What resources/guidelines will you use to help identify, diagnose, and treat diabetes? Give brief overview of how this will apply to your NP practice.

Shadow Health Technical Support
If at any time you have any questions or encounter any technical issues regarding the Digital Clinical Experience, please contact the Shadow Health support specialists by visiting the Learner Support Page at http://support.shadowhealth.com for contact information and hours. You may email the Learner Support team directly at [email protected] at any time or by calling 800.860.3241.

Shadow Health: Focused Exam: Hypertension and Type 2 Diabetes

The purpose of this Shadow Health Focused Exam assignment is to help you achieve Course Learning Outcomes 1-5.

Assignment:
This assignment is a focused exam with a patient who presents with hypertension and type 2 diabetes. You will conduct an interview with Arun Patel using therapeutic communication to determine the appropriate pharmacological therapy for his condition. After the exam, you will select the most appropriate medication for Mr. Patel and educate him on disease management and pharmacologic management. If applicable, you will write a prescription for the selected medication.
What to Submit:
Upon completion of the assignment, submit your completion certificate/lab pass that shows the DCE score to this assignment link..

Shadow Health Grading
All assignments will be graded using the DCE Score. Reopening and multiple attempts are allowed so the student can submit the best score for grading. Each student will submit the “lab pass” showing their DCE score to the designated assignment tab in Blackboard. Grading will be based on the DCE score received on the assignment that correlates with the points allocated in the table below. An incomplete assignment will result in the grade of zero. Faculty will monitor student engagement within the Shadow Health platform to ensure active participation to complete all the assignment requirements.

DCE Score

Points

95-100

90-94

85-89

80-84

Below 79

No submission

Assignment Due Date: Sunday of Week 6

Unit Conclusion
Unit Conclusion

As we wrap up week 6 of Advanced Pharmacology, we recall learning about numerous drugs impacting the endocrine system and diabetes management. We now have lots of experiences understanding drug classes to categorize the mechanisms of actions and subtle differences between in-class drugs. We will continue to focus on building upon our pharmacology knowledge.

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