PICO Question Examples
Evidence-based models use a process for framing a question, locating, assessing, evaluating, and repeating as needed. PICO (T) elements include: Problem/Patient/Population, Intervention/Indicator, Comparison,Outcome, and (optional) Time element or Type of Study.
 Does hand washing among healthcare workers reduce hospital acquired infections?
The question above includes the PICO elements:

 
Example:

P (Problem or Patient orPopulation)
hospital acquired infection

I (intervention/indicator)
hand washing

C (comparison)
no hand washing; other solution; masks

O (outcome of interest)
reduced infection